Regulation of apoA1 gene expression with acidosis: requirement for a transcriptional repressor

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Regulation of apoA1 gene expression with acidosis: requirement for a transcriptional repressor.

Serum apolipoprotein A(1) (apoA(1)) concentration is inversely correlated with the risk of premature atherosclerosis. Serum apoA(1) concentrations are regulated, in part, at the transcriptional level. ApoA(1) mRNA is synthesized primarily in the liver and small intestine, under the direction of a number of signaling molecules and tissue-specific regulatory elements. Previously, we demonstrated ...

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ژورنال

عنوان ژورنال: Journal of Molecular Endocrinology

سال: 2001

ISSN: 0952-5041,1479-6813

DOI: 10.1677/jme.0.0270043